Press reviews


By Carolina Lima | Published October 23, 2025 | 3 min read


In recent years, mental health care has undergone a significant transformation, with digital tools reshaping how therapy is delivered. Among these innovations, virtual cognitive behavioral therapy (eCBT) has emerged as a promising alternative to traditional in-person therapy, offering flexibility, accessibility, and compara...

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By Ana Espino | Published on october 23, 2025 | 3 min read


Brain metastases are a frequent and severe complication of advanced cancers, particularly non–small cell lung cancer (NSCLC) and metastatic breast cancer (MBC). They significantly worsen prognosis and quality of life, while remaining difficult to manage due to the blood–brain barrier (BBB), which limits the penetration...

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By Lila Rouland | Published October 22, 2025 | 3 min read


Triple-negative breast cancer (TNBC) is characterized by the absence of hormonal receptors (ER, PR) and the HER2 protein. This particularity significantly limits targeted therapeutic options, leading to a poor prognosis marked by high recurrence and low overall survival rates. Given the biological heterogeneity of TNBC, global...

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By Ana Espino | Published on october 22, 2025 | 3 min read


Triple-negative breast cancer (TNBC), characterized by the absence of hormonal receptors and HER2 expression, accounts for approximately 15–20% of all breast cancer cases. It is associated with a high risk of recurrence and early metastasis. Among patients who present with residual invasive disease after neoadjuvant ch...

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By Ana Espino | Published on october 21, 2025 | 4 min read


Triple-negative breast cancer (TNBC) is a particularly aggressive form of cancer, characterized by the absence of hormone receptors (ER/PR) and HER2. It primarily affects younger women, progresses rapidly, and carries a high risk of relapse, especially due to the lack of exploitable therapeutic targets. Currently, chemo...

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By Lila Rouland | Published October 21, 2025 | 3 min read


Triple-negative breast cancer (TNBC), lacking hormonal and HER2 receptors, represents an aggressive and heterogeneous subtype. Immune checkpoint inhibitors (ICIs), such as pembrolizumab, have recently shown therapeutic potential; however, only about 20% of metastatic patients respond to monotherapy. This highlights the urgent...

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By Ana Espino | Published on october 20, 2025 | 3 min read


The synchronous development of several primary cancers is a rare but increasingly observed phenomenon, particularly in patients carrying genetic mutations such as BRCA1. In this particular case, the coexistence of triple-negative breast cancer and rectal adenocarcinoma is all the more complex as it may occur in patient...

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By Carolina Lima | Published October 17, 2025 | 3 min read


Breast cancer screening is a cornerstone of early detection, but for women with dense breast tissue, traditional mammography often falls short. To address this challenge, the Breast Screening—Risk Adapted Imaging for Density (BRAID) trial, recently published in The Lancet, offers promising evidence on whether supplemen...

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By Ana Espino | Published on october 17, 2025 | 3 min read


Metastatic HR+/HER2– breast cancer — the most common subtype in postmenopausal women — remains an incurable disease despite advances in endocrine therapy and CDK4/6 inhibitors. Most patients eventually develop secondary resistance, limiting therapeutic options. Alterations in the PI3K/AKT/PTEN pathway, frequently observ...

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By Ana Espino | Published on october 16, 2025 | 2 min read


Metastatic breast cancer (MBC) remains an incurable disease with highly heterogeneous clinical forms. Despite recent advances, standard treatments—hormone therapy, chemotherapy, and immunotherapy—have limitations in the face of secondary resistance, genetic variability of tumors, and the progressive exhaustion of thera...

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By Lila Rouland | Published October 16, 2025 | 3 min read


Metastatic breast cancer relies heavily on amino acids for its growth and survival. These essential nutrients can be synthesized or absorbed directly from circulating serum, making them an attractive metabolic target. While enzymatic inhibition of amino acid biosynthetic pathways has shown limited success in clinical settings...

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By Ana Espino | Published on october 15, 2025 | 2 min read


Metastatic breast cancer (MBC) represents the most advanced stage of the disease and remains incurable despite major therapeutic progress. It is responsible for the majority of breast cancer–related deaths. Current treatments—hormone therapy, chemotherapy, and immunotherapy—extend survival but do not eliminate the disea...

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2025-10-15

Fasting hyperglycemia: a silent cancer risk factor?

Endocrinology and Metabolism Oncology

By Ana Espino | Published on october 15, 2025 | 2 min read


Fasting hyperglycemia (FHG)—defined as elevated blood glucose levels outside of meals—is a common condition, particularly among individuals with type 2 diabetes or metabolic syndrome. Its role in the development of cardiovascular diseases is well established, but its involvement in oncogenesis remains controversial and...

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By Lila Rouland | Published October 14, 2025 | 3 min read


Although breast cancer treatments have greatly improved survival, they also expose patients to an increased risk of cardiovascular toxicity. This toxicity can lead to a significant decline in cardiorespiratory fitness (CRF)—a key component of overall health that is closely linked to both cardiovascular and all-cause mortality...

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By Ana Espino | Published on october 13, 2025 | 3 min read


With the growing number of cancer survivors, care no longer ends with remission. Maintaining quality of life has become a key issue, notably through physical activity, which is recognized for its beneficial effects on fatigue, physical function, mood, and even risk of recurrence.   
However, while exercise...

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